Pregabalin 100mg is a medication commonly used in the management of epilepsy, a neurological disorder characterized by recurrent seizures. Seizures can manifest in various forms, ranging from focal seizures with or without impaired awareness to generalized tonic-clonic seizures. Pregabalin offers several mechanisms of action that contribute to its effectiveness in improving seizure symptoms and overall seizure control. This article explores how Pregabalin 100mg can help improve seizure symptoms, providing insights into its mechanisms of action, clinical efficacy, and considerations for use.

Inhibition of Calcium Channels: Pregabalin binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system (CNS), leading to inhibition of calcium influx into neurons. This inhibition reduces the release of excitatory neurotransmitters such as glutamate, thereby dampening neuronal excitability and hyperexcitability, which are central to the generation and propagation of seizures.